The latest version of DNScrypt-proxy does not use anymore a single configuration file (/etc/conf.d/dnscrypt-proxy) but instead completely relies on systemd.
Configuration is now split in two different files.

[root@arch ~]# cat /etc/systemd/system/multi-user.target.wants/dnscrypt-proxy.service
---
[Unit]
Description=DNSCrypt client proxy
Requires=dnscrypt-proxy.socket

[Install]
Also=dnscrypt-proxy.socket
WantedBy=multi-user.target

[Service]
Type=simple
NonBlocking=true
ExecStart=/usr/bin/dnscrypt-proxy \
    --resolver-address=185.97.7.7:27015 \
    --provider-name=2.dnscrypt-cert.fvz-rec-de-fra-01.dnsrec.meo.ws \
    --provider-key=9FCC:EB74:6856:238D:AC57:428B:DE4F:D9C6:E736:5370:E9F9:5415:3BD3:6EBE:A8C2:FAFE \
    --user=nobody

…and…

[root@arch ~]# cat /etc/systemd/system/dnscrypt-proxy.socket
---
[Unit]
Description=dnscrypt-proxy listening socket
After=network.target

[Socket]
ListenStream=127.0.0.2:53
ListenDatagram=127.0.0.2:53

[Install]
WantedBy=sockets.target